Product No.： CAS NO. 117772-70-0
Specification： 25kg/Drum
Trademark： SerumAPI
Support OEM/ODM： Yes
Mini. Order： 1000KG
Delivery Time： 7~30 Days
Trade Term： FOB,CIF
Payment Term： T/T,L/C
Standard Available： CP,BP,USP,JP
Description of Azithromycin:
Azithromycin is a semi-synthetic 15-membered macrolide antibiotic. White or quasi-white crystalline powder; odorless, bitter; slightly damp. This product is soluble in meth anol, ace tone, chloro form, anhydrous ethanol or dilute hydrochloricacid, and almost insoluble in water.
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Prodcut name
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AZITHROMYCIN DIHYDRATE
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MOQ
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1kg
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CAS No.
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117772-70-0
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Appearance
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crystalline powder
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Molecular Formula
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C38H72N2O12
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Assay
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99%
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Application
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Pharma grade or research purpose
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Packing
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As per your request
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Storage
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Preserve in tight, light-resistant containers in a cool place
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Remarks
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NA
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Custom synthesis
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Available
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Supply Ability
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500kg/month
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CERTIFICATE OF ANALYSIS
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Product Name
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Azithromycin
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Batch No
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22070702
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Manufacturing Date
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JUL.07.2022
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Packing
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25 kg/drum
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Valid until
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JUL.06.2024
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Batch Quantity
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780kg
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Testing Date
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AUG.12.2022
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Analysis No
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COA202209029
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Report date
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AUG.14.2022
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Quality Standard
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USP43
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TESTITEMS
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SPECIFICATION
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RESULT
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Characteristics
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It is white or almost white crystalline powder slightly hygroscopic
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White Crystalline Powder
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Specific Rotation
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-45°~-49° -47°
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ldentification
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IR
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IR spectrum should meet the requirement
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Conforms
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HPLC
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LC chromatogram should meet the requirement.
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Conforms
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PH Value
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9.0~11.0
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10.6
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Crystallinity
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Birefringence and extinction positions
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Conforms
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Water
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4.0%～5.0%
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4.6%
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Residue on lgnition
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≤0.3%
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0.05%
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Related
Substances
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Azaerythromycin A
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≤0.5%
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Not detected
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3-Deoxyazithromycin (azithromycin B)
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≤1.0%
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0.4%
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Azithromycin C(3”-O- demethylazithromycin)
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≤0.5%
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Not detected
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3'-(N,N-Didemethyl) azithromycin(aminoazith romycin)
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≤0.5%
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Not detected
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N-Demethylazithromycin
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≤0.7%
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Not detected
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2-Desethyl-2-propylazithromycin
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≤0.5%
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0.1%
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Azithromycin impurity P
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≤0.2%
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Not detected
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Azithromycin related compound F
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≤0.5%
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Not detected
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3'-N-{[4-(Acetylamino)
phenylJsulfonyl}-3-didemet hylazithromycin
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≤0.5%
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Not detected
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Description:
Azithromycin is a semi-synthetic macrolide antibiotic belonging to the azalide subclass, characterized by a 15-membered lactone ring with a nitrogen insertion that enhances its acid stability and broadens its antimicrobial spectrum. This white to off-white crystalline powder has a molecular formula of C38H72N2O12 and a molecular weight of 749.0 g/mol. The compound demonstrates unique pharmacokinetic properties, including extensive tissue penetration and prolonged half-life (68 hours), allowing for shorter treatment regimens compared to other antibiotics. Azithromycin is sparingly soluble in water but freely soluble in ethanol, , and , with a pKa of 8.74. Its chemical structure features a desosamine sugar and a cladinose sugar attached to the lactone ring, which are crucial for its ribosomal binding activity.
