Elevating NAD+ levels activates pathways related to energy metabolism and longevity; clinical studies show that supplementing NR can reduce systolic blood pressure by approximately 10 mmHg, equivalent to a 25% reduction in the risk of heart attack.

By enhancing NAD+ levels, it provides support for energy-dependent neurons, helping to slow down age-related cognitive decline. Animal experiments have shown that NR has significant anti-inflammatory and neuroprotective effects on neuroinflammatory models such as multiple sclerosis.

Activating PGC-1α-mediated mitochondrial biosynthesis and promoting the formation of new muscle fibers. In the Marfan syndrome mouse model, NR successfully improved the phenotype of muscle atrophy (sarcopenia).

Demonstrates the potential to repair specific tissue damage. Studies have confirmed that NR can effectively treat long-term intestinal damage caused by radiotherapy by reducing oxidative stress, inhibiting cellular aging, and improving the intestinal microbiota.

By optimizing NAD+-dependent circadian rhythm regulation, it may improve sleep structure. A clinical trial is currently underway to verify the impact of daily supplementation of 2000 mg NR on sleep quality in healthy adults aged 40-60.